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Therapy for Melanoma at Oasis of HopeCurrently available chemotherapy drugs have proven to be of minimal benefit in melanoma, which tends to be highly chemoresistant. Hence, the Oasis IRT-C protocol, featuring repeated high-dose infusions of vitamin C, represents a good option for patients with this cancer. This therapy is intended to kill tumor cells selectively by causing severe oxidative stress within the tumor. Intravenous vitamin C therapy at Oasis is distinguished by novel adjunctive features such as ozone autohemotherapy, laetrile therapy and administration of the oxygen-carrier Perftec, which are intended to boost tumor oxygenation, and vitamin K, which helps to catalyze oxidant generation so as to maximize cancer cell kill. The efficacy of vitamin C therapy hinges on transfer of electrons from ascorbate (a form of vitamin C) to oxygen, which generates the oxidant superoxide. This obviously requires adequate tumor levels of oxygen, and vitamin K (menadione) can act as an intermediate in the transfer of electrons from ascorbate to oxygen.
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