RFA’s limitation is obvious: tumors larger than five centimeters (two inches) across won’t be cooked completely. Theoretically, any tumor reachable by a probe could be treated, but the most commonly targeted are in the liver, kidneys, and lungs, as sufficient data proves efficacy there.
(If there are many tumors, RFA is not indicated.) More areas are being researched. LeVeen published his results in 1976; though we still don’t have long-term post-RFA outcomes, preliminary results are encouraging.
With RFA we can treat tumors that can’t be surgically removed due to location or poor health. RFA isn’t cheap, but it’s affordable compared to new drugs; it also can be an outpatient procedure and can be used in conjunction with radiation, chemo, surgery, and alternative agents.